The usual dose of diovan in patients with high blood pressure is 80 to 160 mg once daily. The maximum dose is 320 mg daily. Maximum blood pressure reduction occurs within 4 weeks. For congestive heart failure, the usual dose is 40 mg twice daily. The doses may be increased to 80-160 mg twice daily. The initial dose after a heart attack is 20 mg twice daily. The dose should be increased with a target of 160 mg twice daily if tolerated without side effects.
Drug Class and Mechanism
The chemical name is a proper scientific name for an ingredient of a product. Chemical name of this medicine is VALSARTAN (read as: val-SAR-tan). Valsartan is an oral medication that belongs to a class of drugs, called angiotensin receptor blockers (ARBs) . Other ARBs include irbesartan (Avapro), losartan (Cozaar), and candesartan (Atacand). Angiotensin, formed in the blood by the action of angiotensin converting enzyme (ACE), is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on smooth muscle cells of blood vessels. Angiotensin attachment to the receptors causes the blood vessels to narrow (vasoconstrict) which leads to an increase in blood pressure (hypertension). Valsartan blocks the angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure. Valsartan was approved by the FDA in December of 1996.
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. If you are taking 1 dose daily and do not remember until the next day, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Storage
Diovan should be stored at room temperature, 15-30 degrees C (59-86 degrees F).
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